2019年，GenStar產(chǎn)品共助力SCI文獻(xiàn)300+篇。主要客戶單位包括清華大學(xué)、北京大學(xué)、中國(guó)農(nóng)業(yè)大學(xué)、中科院動(dòng)物所、中科院遺傳所、中山大學(xué)、華南農(nóng)業(yè)大學(xué)、中科院上海巴斯德所、中科院上海生化細(xì)胞所、西北農(nóng)林科技大學(xué)、西安交通大學(xué)、天津大學(xué)、南開(kāi)大學(xué)、南京大學(xué)、東南大學(xué)等。涉及產(chǎn)品涵蓋熒光定量qPCR產(chǎn)品、普通Taq Mix、高保真SuperStar Mix、熱啟動(dòng)HotStart Mix、逆轉(zhuǎn)錄試劑盒、DNA Marker和彩色蛋白Marker等多類產(chǎn)品。

1. YueXu, PingZhou, SenCheng, et al. A Bacterial Effector Reveals the V-ATPase-ATG16L1 Axis that Initiates. CELL. 2019; 178(3): 552-566. IF: 24.38

2. Jingke Xie, Weikai Ge, Nan Li, et al. Efficient base editing for multiple genes and loci in pigs using base editors. NAT COMMUN. 2019; 10: 2852. IF: 12.19

3. RanRan Xing, RanRan Hu, JianXun Han, et al. DNA barcoding and mini-barcoding in authenticating processed animal-derived food: A case study involving the Chinese market. FOOD CHEM. 2019; 309. IF: 5.399

4. Xinming Shen, Wei Liu, Yongjiu Chen, et al. Diagnostic significance of metallothionein members in recognizing cadmium exposure in various organs under low-dose exposure. CHEMOSPHERE. 2019; 229: 32-40. IF: 5.108

5. Le Li, Youxiang Mao, Lina Zhao, et al. p53 regulation of ammonia metabolism through urea cycle controls polyamine biosynthesis. Nature. volume 567, pages253–256(2019). Doi.org/10.1038/s41586-019-0996-7 IF: 41.577

6. Yao Wang, Shaochun Yuan, Xin Jia, et al. Mitochondria-localised ZNFX1 functions as a dsRNA sensor to initiate antiviral responses through MAVS. Nat Cell Biol. 2019.21:1346–1356 IF: 20.06

7. Huifang Xian, Shuai Yang, Shouheng Jin, et al. LRRC59 modulates type I interferon signaling by restraining the SQSTM1/p62-mediated autophagic degradation of pattern recognition receptor DDX58/RIG-I. Autophagy, 2019(5). IF: 11.059

8. Chuanxia Zhang, Shubiao Ye, Jianjiao Ni, et al. STING signaling remodels the tumor microenvironment by antagonizing myeloid-derived suppressor cell expansion. Cell Death Differ. 2019.26(11):2314-2328. IF: 8.086

9. Tao Liu, Yutao Zhou, Liqiu Wang, Liyue Li, Qing Bao, Shuo Tian, Meixin Chen, Hexin Chen, Jun Cui and Chunwei Li. NOD-like receptor family, pyrin domain containing 3 (NLRP3) contributes to inflammation, pyroptosis, and mucin production in human airway epithelium on rhinovirus infection. J Allergy Clin Immunol. 2019.144(3):777-787. IF: 14.11

10. Rui Shen, ZhiYu Ning, YuXuan Lan, et al. Manipulation of polyhydroxyalkanoate granular sizes in Halomonas bluephagenesis. METAB ENG. 2019; 54: 117-126. IF: 8.78

11. Jiajun Nie, Zhiyuan Yin, Zhengpeng Li, et al. A small cysteine‐rich protein from two kingdoms of microbes is recognized as a novel pathogen‐associated molecular pattern. NEW PHYTOL. 2019;. IF: 7.17

12. MingHao Liu, Houxiang Kang, Yucheng Xu, et al. Genome‐wide association study identifies an NLR gene that confers partial resistance to Magnaporthe oryzae in rice. PLANT BIOTECHNOL J. 2019; https://doi.org/10.1111/pbi.13300. IF: 6.88

13. Guan Lian, Xiaopeng Li, Linqi Zhang, et al. Macrophage metabolic reprogramming aggravates aortic dissection through the HIF1α-ADAM17 pathway. EBIOMEDICINE. 2019; 49: 291-304. IF: 6.680

14. Wenjun Deng, Riqing Li, Yiwei Xu, et al. A lipid transfer protein variant with a mutant eight-cysteine motif causes photoperiod- and thermo-sensitive dwarfism in rice. J EXP BOT. 2019. IF: 5.47

15. Yong Tang, Hailin Tu, Jie Zhang, et al. K63-linked ubiquitination regulates RIPK1 kinase activity to prevent cell death during embryogenesis and inflammation. NAT COMMUN. 2019; 10: 4157. IF: 12.19

16. Yong Chen, XinYu Chen, He Tong Du, et al. Chromosome engineering of the TCA cycle in Halomonas bluephagenesis for production of copolymers of 3-hydroxybutyrate and 3-hydroxyvalerate (PHBV). METAB ENG.2019; 54: 69-83. IF: 8.78

17. TaoLiu, Yu TaoZhou, Li QiuWang, et al. NOD-like receptor family, pyrin domain containing 3 (NLRP3) contributes to inflammation, pyroptosis, and mucin production in human airway epithelium on rhinovirus infection. J ALLERGY CLIN IMMUN. 2019; 144(3):777-787. IF: 6.87

18. Yong Rao, YuTing Lu, Chan Li, et al. Bouchardatine analogue alleviates non‐alcoholic hepatic fatty liver disease/non‐alcoholic steatohepatitis in high‐fat fed mice by inhibiting ATP synthase activity. BRIT J PHARMACOL. 2019; 176: 2877-2893. IF: 6.538

19. Shuai You, Chen Xie, Rui Ma, et al. Improvement in catalytic activity and thermostability of a GH10 xylanase and its synergistic degradation of biomass with cellulase. BIOTECHNOL BIOFUELS. 2019; 12: 278. IF: 5.84

20. Xiaogang Wang, Xiukai Cao, Dong Dong. Circular RNA TTN Acts As a miR-432 Sponge to Facilitate Proliferation and Differentiation of Myoblasts via the IGF2/PI3K/AKT Signaling Pathway. MOL THER-NUCL ACIDS. 2019; 18: 966-980. IF: 5.81

21. XianChan Wang, Rui Zheng, Qiong Yao, et al. Effects of fluoride on the histology, lipid metabolism, and bile acid secretion in liver of Bufo gargarizans larvae. ENVIRON POLLUT. 2019; 254. IF: 5.714

22. BoXun Zhao, QiXi Wu, Adam YongXin Ye, et al. Somatic LINE-1 retrotransposition in cortical neurons and non-brain tissues of Rett patients and healthy individuals. PLOS GENET. 2019. IF: 5.57

23. Dandan Yang, Xueqiang Zhao, Xin Lin. Bcl10 is required for the development and suppressive function of Foxp3+ regulatory T cells. CELL MOL IMMUNOL. 2019. IF: 5.23

24. JiaGui Song, TianZhuo Wang, XiaoChun Chi. Kindlin-2 Inhibits the Hippo Signaling Pathway by Promoting Degradation of MOB1. CELL REP. 2019; 29(11): 3664-3677. IF: 8.04

25. ChunXia Wang, ChuangYe Qi, JinHong Luo, et al. Characterization of LRL5 as a key regulator of root hair growth in maize. PLANT J. 2019, 98: 71-82. doi:10.1111/tpj.14200. IF: 5.91

26. Hui Mai, WeiHao Fan, Yan Wang, et al. Intranasal Administration of miR-146a Agomir Rescued the Pathological Process and Cognitive Impairment in an AD Mouse Model. MOL THER-NUCL ACIDS. 2019; 18: 681-695. IF: 5.81

27. ChunXia Wang, ChuangYe Qi, JinHong Luo, et al. Characterization of LRL5 as a key regulator of root hair growth in maize. Plant J. 2019.98(1):71-82. IF: 5.726

28. XianChan Wang, Rui Zheng, Qiong Yao, et al. Effects of fluoride on the histology, lipid metabolism, and bile acid secretion in liver of Bufo gargarizans larvae. ENVIRON POLLUT. 2019; 254. IF: 5.714

29. JingJing Lu, YanLing Ma, GuanLan Xing, et al. Revelation of microalgae's lipid production and resistance mechanism to ultra-high Cd stress by integrated transcriptome and physiochemical analyses. ENVIRON POLLUT. 2019; 250: 186-195. IF: 5.714

30. ChuXiao Liu, Xiang Li, Fang Nan, et al. Structure and Degradation of Circular RNAs Regulate PKR Activation in Innate Immunity. Cell (2019), https://doi.org/10.1016/j.cell.2019.03.046 IF: 30.4

31. ChuXiao Liu, Xiang Li, Fang Nan, et al. Structure and Degradation of Circular RNAs Regulate PKR Activation in Innate Immunity. CELL. 2019; 177(4): 865-880. IF: 24.38

32. LiangZhong Yang, Yang Wang, SiQi Li, et al. Dynamic Imaging of RNA in Living Cells by CRISPR-Cas13 Systems. MOL CELL. 2019; 76(6): 981-997. IF: 11.82

33. RunWen Yao, Guang Xu, Ying Wang, et al. Nascent Pre-rRNA Sorting via Phase Separation Drives the Assembly of Dense Fibrillar Components in the Human Nucleolus. MOL CELL.2019; 76(5): 767-783. IF: 11.82

34. YuanMei Liang, Jie Tang, YiFan Luo, et al. Thermosynechococcus as a thermophilic photosynthetic microbial cell factory for CO2 utilisation. BIORESOURCE TECHNOL. 2019; 278: 255-265. IF: 6.669

35. YunPeng Xu, ZhiDong He, MengJiao Song, et al. A microRNA switch controls dietary restriction‐induced longevity through Wnt signaling. EMBO REP. 2019, 20:e46888https://doi.org/10.15252. IF: 5.28

36. YuanYuan Fu, Liang Hong, JieCheng Xu, et al. Discovery of a small molecule targeting autophagy via ATG4B inhibition and cell death of colorectal cancer cells in vitro and in vivo. AUTOPHAGY. 2019; 15(2): 295-311. DOI: 10.1080/15548627.2018.1517073. IF: 7.01

37. Li Mi, Jing Sui, YaFeng Wu, et al. Bioinspired in Vitro Lung Airway Model for Inflammatory Analysis via Hydrophobic Nanochannel Membrane with Joint Three-Phase Interface. Anal. Chem. 2019, 91, 24, 15804-15810. IF: 6.38

38. YiRan Zhou, BeiLi Chen, Lin Li, et al. Novel alanyl-tRNA synthetase 2 (AARS2) homozygous mutation in a consanguineous Chinese family with premature ovarian insufficiency. FERTIL STERIL. 2019; 112(3): 569-576. IF: 5.411

39. YongTai Bai, WeiBin Wang, SiYu Li, et al. C1QBP Promotes Homologous Recombination by Stabilizing MRE11 and Controlling the Assembly and Activation of MRE11/RAD50/NBS1 Complex. Molecular Cell. 2019; 75（6）: 1299-1314. IF: 11.82

40. MingHao Hu, TianYing Wu, Qiong Huang, et al. New substituted quinoxalines inhibit triple-negative breast cancer by specifically downregulating the c-MYC transcription. NUCLEIC ACIDS RES. 2019; 47(20): 10529–10542. IF: 11.14

41. WangLong Zhang, HeiDi QunHui Xie, YunPing Li, et al. Characterization of the Aryl Hydrocarbon Receptor (AhR) Pathway in Anabas testudineus and Mechanistic Exploration of the Reduced Sensitivity of AhR2a. Environ. Sci. Technol. 2019, 53, 21, 12803-12811. IF: 7.38

42. MeiJie Qu, JiaJi Pan, LiPing Wang, et al. MicroRNA-126 Regulates Angiogenesis and Neurogenesis in a Mouse Model of Focal Cerebral Ischemia. MOL THER-NUCL ACIDS. 2019; 16: 15-25. IF: 5.81

43. MingXing Chang, MianGu, YuWei Xia, et al. OsPHT1;3 Mediates Uptake, Translocation, and Remobilization of Phosphate under Extremely Low Phosphate Regimes. PLANT PHYSIOL. 2019; 179(2): 656-670.DOI: 10.1104/pp.18.01097. IF: 6.37

44. YuanYuan Fu, Liang Hong, JieCheng Xu, et al. Discovery of a small molecule targeting autophagy via ATG4B inhibition and cell death of colorectal cancer cells in vitro and in vivo, Autophagy, (2019)15:2, 295-311, DOI: 10.1080/15548627.2018.1517073. IF: 11.1

45. JiaZheng Lai, GuanJun Deng, ZhiHong Sun, et al. Scaffolds biomimicking macrophages for a glioblastoma NIR-Ib imaging guided photothermal therapeutic strategy by crossing Blood-Brain Barrier. BIOMATERIALS. 2019; 211: 48-56. IF: 10.273

46. FeiFei Yu, Qi Xie. Approaches to Identify Protein Ubiquitination Sites in Plants. Methods in Molecular Biology. 2019; 2026: 85-93. IF: 13.9

47. Sabarathinam Shanmugam, ChongRan Sun, ZiChuang Chen, et al. Enhanced bioconversion of hemicellulosic biomass by microbial consortium for biobutanol production with bioaugmentation strategy. BIORESOURCE TECHNOL. 2019; 279: 149-155. IF: 6.669

48. SaiSai Guo, HaoWen Ran, DaKe Xiao, et al. NT5DC2 promotes tumorigenicity of glioma stem-like cells by upregulating fyn. CANCER LETT. 2019; 454: 98-107. IF: 6.508

49. LiHeng Tuan, LiJen Lee. Microglia-mediated synaptic pruning is impaired in sleep-deprived adolescent mice. NEUROBIOL DIS. 2019; 130. IF: 5.36

50. ShuangHe Cao, XuMei Luo, Li Xie, et al. The florigen interactor BdES43 represses flowering in the model temperate grass Brachypodium distachyon. PLANT J. 2019, doi:10.1111/tpj.14622. IF: 5.91

51. XingWang Zhao, HengYi Xie, Meng Zhao, et al. Fc receptor–like 1 intrinsically recruits c-Abl to enhance B cell activation and function. SCI ADV. 2019;Vol. 5, no. 7, eaaw0315.DOI: 10.1126. IF: 13.05

52. Bing Jiang, RuoFei Zhang, JianLin Zhang, et al. GRP78-targeted ferritin nanocaged ultra-high dose of doxorubicin for hepatocellular carcinoma therapy. THERANOSTICS. 2019; 9(8): 2167–2182. IF: 8.12

53. Obayed Raihan, Afrina Brishti, QinLi, et al. SFRS11 Loss Leads to Aging-Associated Cognitive Decline by Modulating LRP8 and ApoE. CELL REP. 2019;28: 78-90. IF: 8.04

54. CuiCui Ji, HongYu Zhao, DongFang Li, et al. Role of Wdr45b in maintaining neural autophagy and cognitive function. AUTOPHAGY.DOI: 10.1080/15548627.2019.1632621. IF: 7.01

55. XiaoFan Xiong, Lingyu Zhang, MeiYang Fan, et al. β-Endorphin Induction by Psychological Stress Promotes Leydig Cell Apoptosis through p38 MAPK Pathway in Male Rats. Cells. 2019, 8, 1265. IF: 5.77

56. PengSheng Chen, Huan Wang, WenHao Zhang, et al. Loss of BAP1 Results in Growth Inhibition and Enhances Mesenchymal–Epithelial Transition in Kidney Tumor Cells. MOL CELL PROTEOMICS. 2019; 18 (7): 1320-1329. IF: 5.41

57. Yong Rao, YuTing Lu, Chan Li, et al. Bouchardatine analogue alleviates non‐alcoholic hepatic fatty liver disease/non‐alcoholic steatohepatitis in high‐fat fed mice by inhibiting ATP synthase activity. BRIT J PHARMACOL. 2019; 176: 2877-2893. IF: 6.538

58. Zining Wang, Jiemin Chen, Jie Hu, et al. cGAS/STING axis mediates a topoisomerase II inhibitor–induced tumor immunogenicity. J CLIN INVEST. 2019;129(11):4850–4862. IF: 10.49

59. HanJun Hao, MengMeng Sun, PengYong Li, et al. In Situ Growth of a Cationic Polymer from the N-Terminus of Glucose Oxidase To Regulate H2O2 Generation for Cancer Starvation and H2O2 Therapy. ACS APPL MATER INTER.2019; 11(10): 9756-9762. IF: 8.69

60. HongHui Wang, Yu Zhang, Feng Tang, et al. Rab23/Kif17 regulate meiotic progression in oocytes by modulating tubulin acetylation and actin dynamics. DEVELOPMENT. 2019; 146: dev171280 doi: 10.1242/dev.171280. IF: 5.24

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