GenStar 產(chǎn)品第三季度高光時刻來嘍~
據(jù)知了窩平臺數(shù)據(jù)統(tǒng)計，2023 年第三季度使用 GenStar 產(chǎn)品發(fā)表的 SCI 文章近 100 篇，影響因子（Impact factor, IF）分布如圖所示：
平均 IF 為 7.1， IF＞5 的文章占比高達 54 %， 最高 IF 為 37.3，影響因子為 37.3 的文章發(fā)表在 Molecular Cancer 上，其中用到 GenStar 的 PCR 系列明星產(chǎn)品-紅星 Mix（Cat#A012）。第三季度 GenStar 產(chǎn)品發(fā)表文章數(shù)量，qPCR 系列產(chǎn)品仍位居第一，發(fā)表文章數(shù)量 25 篇，平均 IF 為 8.2，最高 IF 為 23.2。其次為核酸提取系列產(chǎn)品，發(fā)表文章數(shù)量 22 篇。
GenStar 取得的所有成績和進步，都離不開各位新老客戶的支持和認可，我們也會繼續(xù)為大家提供更優(yōu)質的產(chǎn)品和服務。
01 qPCR 產(chǎn)品
1. Wang Yu, Yue Jiaolin, Yang Nan,et al. An ERAD-related ubiquitin-conjugating enzyme boosts broad-spectrum disease resistance and yield in rice. Nature Food. 2023.Aug. IF=23.2（Cat#A301）
2. Zheng Leiying, Wu Huilan, Wang Anbin,et al. The SOD7/DPA4–GIF1 module coordinates organ growth and iron uptake in Arabidopsis. Nature Plants. 2023.Aug. IF=18（Cat#A301）
3. Jiana Huang, Peigen Chen, Lei Jia,et al. Multi-Omics Analysis Reveals Translational Landscapes and Regulations in Mouse and Human Oocyte Aging. Advanced Science. 2023.Jul. IF=15.1（Cat#A311）
4. Liuzhi Hao, Shuwen Huang, Tongling Huang,et al. Bone targeting miR-26a loaded exosome-mimetics for bone regeneration therapy by activating Wnt signaling pathway. Chemical Engineering Journal. 2023.Jul. IF=15.1（Cat#A301）
5. Shengping Shang, Guangli Liu, Song Zhang,et al. A fungal CFEM-containing effector targets NPR1 regulator NIMIN2 to suppress plant immunity. Plant Biotechnology Journal. 2023.Aug. IF=13.8（Cat#A311）
6. Huaji Jiang, Yingchao Xie, Jiansen Lu,et al. Pristimerin suppresses AIM2 inflammasome by modulating AIM2-PYCARD/ASC stability via selective autophagy to alleviate tendinopathy. Autophagy. 2023.Aug. IF=13.3（Cat#A324）
7. Zhijun Lin, Mengyao Liu, Wei Xing,et al. A near-infrared fluorescence-enhancing plasmonic biosensing microarray identifies soluble PD-L1 and ICAM-1 as predictive checkpoint biomarkers for cancer immunotherapy. Biosensors & Bioelectronics. 2023.Aug. IF=12.6（Cat#A301）
8. Jia-Nan Song, Kun Liu, Jie Mei,et al. Defined Surface Physicochemical Cues Inhibit M1 Polarization of Human Macrophages Using Colloidal Self-Assembled Patterns. Acs Applied Materials & Interfaces. 2023.Jul. IF=9.5（Cat#A301）
9. Liu Chong, Zhao Xue-Min, Wang Qiao,et al. Astrocyte-derived SerpinA3N promotes neuroinflammation and epileptic seizures by activating the NF-κB signaling pathway in mice with temporal lobe epilepsy. Journal Of Neuroinflammation. 2023.Jul. IF=9.3（Cat#A304）
10. Cui Guina, Zhou Jingxuan, Sun Jiatong,et al. WD repeat domain 82 (Wdr82) facilitates mouse iPSCs generation by interfering mitochondrial oxidative phosphorylation and glycolysis. Cellular And Molecular Life Sciences. 2023.Jul. IF=8（Cat#A303）
11. Wu Tong, Yang Zhongyuan, Chen Weichao,et al. miR-30e-5p-mediated FOXD1 promotes cell proliferation by blocking cellular senescence and apoptosis through p21/CDK2/Rb signaling in head and neck carcinoma. Cell Death Discovery. 2023.Aug. IF=7（Cat#A301）
12. Cui Shuang-Shuang, Zhang Ping, Sun Lu,et al. Mucin1 induced trophoblast dysfunction in gestational diabetes mellitus via Wnt/β-catenin pathway. Biological Research. 2023.Aug. IF=6.7（Cat#A304）
13. Yuanyuan Hong, Yinhui Sun, Xuan Zhang,et al. Screening and Identification of Garlic Leaf Blight (Pleospora herbarum)-Resistant Mutants Induced by Ethyl Methane Sulphonate. International Journal Of Molecular Sciences. 2023.Jul. IF=5.6（Cat#A301）
14. Lingli Tang, Yuhua He, Bin Liu,et al. Genome-Wide Identification and Characterization Analysis of WUSCHEL-Related Homeobox Family in Melon (Cucumis melo L.). International Journal Of Molecular Sciences. 2023.Aug. IF=5.6（Cat#A301）
15. Shuaini Yang, Jiajia Zeng, Wenlian Hao,et al. IL-21/IL-21R Promotes the Pro-Inflammatory Effects of Macrophages during C. muridarum Respiratory Infection. International Journal Of Molecular Sciences. 2023.Aug. IF=5.6（Cat#A301）
16. Jun Wang, Qiu-Tong Liu, Dan-Yang Shen,et al. Network pharmacology analysis of the active ingredients of Corydalis hendersonii Hemsl. and their effects on eliminating neuroinflammation and improving motor functions in MPTP-intoxicated mice. Journal Of Ethnopharmacology. 2023.Aug. IF=5.4（Cat#A301）
17. MuLan Bao, RenGui Bade, Hua Liu,et al. Astragaloside IV against Alzheimer's disease via microglia-mediated neuroinflammation using network pharmacology and experimental validation. European Journal Of Pharmacology. 2023.Aug. IF=5（Cat#A301）
18. Mei-lan Lin, Fei Lu, Xin Zhou,et al. The adaptation of root cell wall pectin to copper toxicity in two citrus species differing in copper tolerance: remodeling and responding. Tree Physiology. 2023.Jul. IF=4（Cat#A301）
19. Zhuang Jing, Fan Jianjun, Zhu Lihuan,et al. miR-452-5p suppressed the metastasis of Non-small cell lung cancer through regulating Moesin. Journal Of Cancer. 2023.Jul. IF=3.9（Cat#A301）
20. Jie Ling, Zhijie Tang, Wei Yang,et al. Pygo2 activates BRPF1 via Pygo2–H3K4me2/3 interaction to maintain malignant progression in colon cancer. Experimental Cell Research. 2023.Jul. IF=3.7（Cat#A301）
21. Zhang Yang, Chao Fengmei, Lv Lihua,et al. Hsa_circ_0041150 serves as a novel biomarker for monitoring chemotherapy resistance in small cell lung cancer patients treated with a first-line chemotherapy regimen. Journal Of Cancer Research And Clinical Oncology. 2023.Aug. IF=3.6（Cat#A301）
22. Tingchu Wu, Bingbing Sun, Kaiyu Lu,et al. The MEF2 homolog of Penaeus vannamei is essential for maintaining the WSSV latent infection. Gene. 2023.Jul. IF=3.5（Cat#A311）
23. Xi Wu, Degang Zhao,,et al. Cloning, Characterization, and Functional Analysis of EuTIL1, a Gene-Encoding Temperature-Induced Lipocalin in Eucommia ulmoides Oliv. Horticulturae. 2023.Aug. IF=3.1（Cat#A301）
24. Qinghua Fu, Peng Wang, Yurou Zhang,et al. Effects of Dietary Inclusion of Asiaticoside on Growth Performance, Lipid Metabolism, and Gut Microbiota in Yellow-Feathered Chickens. Animals. 2023.Aug. IF=3（Cat#A301）
25. Xing Zhang, JingJing Liu, ZhongHua Hao,et al. Autophagy and Apoptosis in MAC-T Cells Are Regulated through AMPK/mTOR/ULK1 Pathway Signaling. Acs Agricultural Science & Technology. 2023.Jul. IF=2.5（Cat#A304）
02 PCR 系列產(chǎn)品
1. Song Runjie, Guo Peilan, Ren Xin,et al. A novel polypeptide CAPG-171aa encoded by circCAPG plays a critical role in triple-negative breast cancer. Molecular Cancer. 2023.Jul. IF=37.3（Cat#A012）
2. Jianan Zhao, Chuanrong Zhao, Fangfang Yang,et al. DNMT1 mediates the disturbed flow-induced endothelial to mesenchymal transition through disrupting β-alanine and carnosine homeostasis. Theranostics. 2023.Aug. IF=12.4（Cat#A012）
3. Liping Chen, Qiuhua Li, Ming Wang,et al. ZmCOP1 Regulates Maize Mesocotyl Length and Plant Height through the Phytohormone Pathways. Life-Basel. 2023.Jul. IF=3.2（Cat#A012）
4. Minmin Feng, Zhenbiao Xu, Dandan Yin,et al. Toxic effects of sodium dodecyl sulfate on planarian Dugesia japonica. Peerj. 2023.Jul. IF=2.7（Cat#A015）
03 反轉錄系列產(chǎn)品
1. Kaikai Zhang, Jianzheng Yang, Lijian Chen,et al. Gut Microbiota Participates in Polystyrene Microplastics-Induced Hepatic Injuries by Modulating the Gut–Liver Axis. Acs Nano. 2023.Jul. IF=17.1（Cat#A230）
2. Tian Zhao, Jiaojiao Zhang, Hong Lei,et al. NRF1-mediated mitochondrial biogenesis antagonizes innate antiviral immunity. Embo Journal. 2023.Jul. IF=11.4（Cat#A214）
3. Tao Hai-Ping, Lu Teng-Fei, Li Shuang,et al. Pancreatic lipase-related protein 2 is selectively expressed by peritubular myoid cells in the murine testis and sustains long-term spermatogenesis. Cellular And Molecular Life Sciences. 2023.Jul. IF=8（Cat#A224）
4. Wei Wang, Shou-Kai Wang, Qi Wang,et al. Diclofenac and eugenol hybrid with enhanced anti-inflammatory activity through activating HO-1 and inhibiting NF-κB pathway in vitro and in vivo. European Journal Of Medicinal Chemistry. 2023.Jul. IF=6.7（Cat#A223）
5. Jing Wu, Funa Zhang, Haixia Yu,et al. Anti-Melanogenic and Antioxidant Activity of Bifidobacterium longum Strain ZJ1 Extracts, Isolated from a Chinese Centenarian. International Journal Of Molecular Sciences. 2023.Aug.IF=5.6（Cat#A214）
6. Xuemei Wang, Fengni Liang, Zhaoyuan Dai,et al. Combination of Coptis chinensis polysaccharides and berberine ameliorates ulcerative colitis by regulating gut microbiota and activating AhR/IL-22 pathway. Journal Of Ethnopharmacology. 2023.Aug. IF=5.4（Cat#A214）
7. Man-Yu Xiao, Fang-Fang Li, Peng Xie,et al. Gypenosides suppress hepatocellular carcinoma cells by blocking cholesterol biosynthesis through inhibition of MVA pathway enzyme HMGCS1. Chemico-Biological Interactions. 2023.Aug. IF=5.1（Cat#A212）
8. Luo Yizhuo, Yang Yunlong, Wang Wenru,et al. Aloe-emodin inhibits African swine fever virus replication by promoting apoptosis via regulating NF-κB signaling pathway. Virology Journal. 2023.Jul. IF=4.8（Cat#A223）
9. Jie Wang, Zhipeng Yuan, Delin Li,et al. Transcriptome Analysis Revealed the Potential Molecular Mechanism of Anthocyanidins’ Improved Salt Tolerance in Maize Seedlings. Plants-Basel. 2023.Jul. IF=4.5（Cat#A224）
10. Xu Menglin, Zuo Dongyun, Wang Qiaolian,et al. Identification and molecular evolution of the GLX genes in 21 plant species: a focus on the Gossypium hirsutum. Bmc Genomics. 2023.Aug. IF=4.4（Cat#A214）
11. Wang Haiyang, Zhai Lulu, Wang Shouwen,et al. Identification of R2R3-MYB family in blueberry and its potential involvement of anthocyanin biosynthesis in fruits. Bmc Genomics. 2023.Aug. IF=4.4(Cat#A224)
12. Yan-qi Yang, Rui-fang Sun, Pan Ge,et al. GRPR down-regulation inhibits spermatogenesis through Ca2+ mediated by PLCβ/IP3R signaling pathway in long-term formaldehyde-exposed rats. Food And Chemical Toxicology. 2023.Aug. IF=4.3（Cat#A224）
13. Mei Huang, Jian-Yu Meng, Lv Zhou,et al. Expression and function of opsin genes associated with phototaxis in Zeugodacus cucurbitae Coquillett (Diptera: Tephritidae). Pest Management Science. 2023.Jul. IF=4.1（Cat#A214）
14. Yi Wei, Yongfa Liu, Guang Li,et al. Effects of quercetin and genistein on egg quality, lipid profiles, and immunity in laying hens. Journal Of The Science Of Food And Agriculture. 2023.Aug. IF=4.1（Cat#A223）
15. Jiang Ting, Chen Jinfeng, Wang Zhenzhen,et al. miR-4796 enhances the sensitivity of breast cancer cells to ionising radiation by impairing the DNA repair pathway. Breast Cancer. 2023.Jul. IF=4（Cat#A214）
16. Jinkui Sun, Yong Ruan, Jiali Xu,et al. Effect of Bovine MEF2A Gene Expression on Proliferation and Apoptosis of Myoblast Cells. Genes. 2023.Jul. IF=3.5（Cat#A214）
17. Zeping Shen, Tingting Zuo, Hailin Xia,et al. Synthetic CsCEP3 Peptide Attenuates Salinity Stress via ROS and ABA Signaling in Cucumber Primary Root. Horticulturae. 2023.Aug. IF=3.1（Cat#A224）
18. Jia Yiming, Huo Xin, Wu Leilei,et al. circSNTB2 and CUL4A Induces Dysfunction of Nucleus Pulposus Cells by Competitively Binding miR-665. Biochemical Genetics. 2023.Jul. IF=2.4（Cat#A212）
04 蛋白電泳&分析&蛋白純化系列產(chǎn)品
1. Lu Yu, Hang Wen, Chang Liu,et al. Embryonic stem cell-derived extracellular vesicles rejuvenate senescent cells and antagonize aging in mice. Bioactive Materials. 2023.Jul. IF=18.9（Cat#E162）
2. Xin Fan, Huimin Guo, Aurore Richel,et al. Preparation, physicochemical properties, and formation mechanism of quinoa self-assembled peptide-based hydrogel. Food Hydrocolloids. 2023.Aug. IF=10.7（Cat#M223）
3. Chen Guanglei, Sun Lisha, Gu Xi,et al. FSIP1 enhances the therapeutic sensitivity to CDK4/6 inhibitors in triple-negative breast cancer patients by activating the Nanog pathway. Science China-Life Sciences. 2023.Jul. IF=9.1（Cat#E162）
4. Ying Yang, Tian Tian, Shan Li,et al. LncRNA 220: A Novel Long Non-Coding RNA Regulates Autophagy and Apoptosis in Kupffer Cells via the miR-5101/PI3K/AKT/mTOR Axis in LPS-Induced Endotoxemic Liver Injury in Mice. International Journal Of Molecular Sciences. 2023.Jul. IF=5.6（Cat#E121）
5. Yue Yin, Xinping Xu, Dayan Li,et al. Role of Cx43 in iPSC-CM Damage Induced by Microwave Radiation. International Journal Of Molecular Sciences. 2023.Aug. IF=5.6（Cat#E151）
6. Khadija Javed, Yong Wang, Humayun Javed,et al. Tomato Aphid (Aphis gossypii) Secreted Saliva Can Enhance Aphid Resistance by Upregulating Signaling Molecules in Tomato (Solanum lycopersicum). International Journal Of Molecular Sciences. 2023.Aug. IF=5.6（Cat#M223）
7. Xiaoyang Qin, Yan Long, Xue Bai,et al. The disordered C terminus of ALKBH5 promotes phase separation and paraspeckles assembly. Journal Of Biological Chemistry. 2023.Jul. IF=4.8（Cat#M221）
8. Md. Akibul Hasan Bakky, Ngoc Tuan Tran, Yongsheng Zhang,et al. Effects of dietary supplementation of Gracilaria lemaneiformis-derived sulfated polysaccharides on the growth, antioxidant capacity, and innate immunity of rabbitfish (Siganus canaliculatus). Fish & Shellfish Immunology. 2023.Jul. IF=4.7（Cat#E162）
9. Yalei Zhao, Fen Zhang, Xiaoli Zhang,et al. Transcriptomic analysis of hepatocytes reveals the association between ubiquitin-specific peptidase 1 and yes-associated protein 1 during liver regeneration. Regenerative Therapy. 2023.Jul. IF=4.3（Cat#E121）
05 核酸提取/純化系列產(chǎn)品
1. Rong Hao, Wenkun Zhou, Jingrui Li,et al. On salt stress, PLETHORA signaling maintains root meristems. Developmental Cell. 2023.Jul. IF=11.8（Cat#P118）
2. Ziyi Niu, Yutian Liu, Yaxi Wang,et al. Impairment of bile acid metabolism and altered composition by lead and copper in Bufo gargarizans tadpoles. Science Of The Total Environment. 2023.Jul. IF=9.8（Cat#P118）
3. Xinyi Li, Kaiyue Li, Jiayi Li,et al. Effects of perchlorate and exogenous T4 on growth, development and tail resorption of Rana chensinensis. Environmental Pollution. 2023.Aug. IF=8.9（Cat#P118）
4. Shao Jiahao, Wang Meigui, Zhang Anjing,et al. Interference of a mammalian circRNA regulates lipid metabolism reprogramming by targeting miR-24-3p/Igf2/PI3K-AKT-mTOR and Igf2bp2/Ucp1 axis. Cellular And Molecular Life Sciences. 2023.Aug. IF=8（Cat#D111）
5. Kaina Zhang, Yeqing Zheng, Gaowa Bao,et al. Flt3 Activation Mitigates Mitochondrial Fragmentation and Heart Dysfunction through Rebalanced L-OPA1 Processing by Hindering the Interaction between Acetylated p53 and PHB2 in Cardiac Remodeling. Antioxidants. 2023.Aug. IF=7（Cat#P118）
6. Mengjie Liu, Chaofan Li, Jingkun Qu,et al. Baicalein enhances immune response in TNBC by inhibiting leptin expression of adipocytes. Cancer Science. 2023.Jul. IF=5.7（Cat#P118）
7. Jiagui Guo, Yan Yang, Tingting Wang,et al. Analysis of Raffinose Synthase Gene Family in Bread Wheat and Identification of Drought Resistance and Salt Tolerance Function of TaRS15-3B. International Journal Of Molecular Sciences. 2023.Jul. IF=5.6（Cat#P118）
8. Yinghui Ye, Yulou Luo, Tong Guo,et al. Leveraging senescence-oxidative stress co-relation to predict prognosis and drug sensitivity in breast invasive carcinoma. Frontiers In Endocrinology. 2023.Aug. IF=5.2（Cat#P118）
9. Hui Xia, Ying Wang, Xiangling Shi,et al. Beneficial Effects of Dietary Flaxseed Oil through Inflammation Pathways and Gut Microbiota in Streptozotocin-Induced Diabetic Mice. Foods. 2023.Aug. IF=5.2（Cat#P118）
10. Xintao Jing, Cong Han, Qian Li,et al. IGF2BP3-EGFR-AKT axis promotes breast cancer MDA-MB-231 cell growth. Biochimica Et Biophysica Acta-Molecular Cell Research. 2023.Jul. IF=5.1（Cat#P118）
11. Jie DENG, Zi-e WANG, Wen-yun LI,et al. WRKY11 up-regulated dirigent expression to enhance lignin/lignans accumulation in Lilium regale Wilson during response to Fusarium wilt1. Journal Of Integrative Agriculture. 2023.Jul. IF=4.8（Cat#P118）
12. Jiahao MO, Jun Xiang, Jiang LI,et al. Natural Magnolol ameliorates coccidiosis infected with Eimeria tenella by affecting antioxidant, anti-inflammatory, and gut microbiota of chicks. Poultry Science. 2023.Aug. IF=4.4（Cat#P118）
13. Dongjing Wen, Jiayu Xie, Yao Yuan,et al. The endogenous antioxidant ability of royal jelly in Drosophila is independent of Keap1/Nrf2 by activating oxidoreductase activity. Insect Science. 2023.Aug. IF=4（Cat#P118）
14. Zhaopeng Li, Deyong Bu, Xiaobin Wang,et al. Chidamide and Oxaliplatin Synergistically Inhibit Colorectal Cancer Growth by Regulating the RPS27A-MDM2-P53 Axis. Oncotargets And Therapy. 2023.Aug. IF=4（Cat#P118）
15. Zijun Zheng, Huiping Li, Runjiao Yang,et al. Role of the membrane-spanning 4A gene family in lung adenocarcinoma. Frontiers In Genetics. 2023.Jul. IF=3.7（Cat#P118）
16. Xiaohui Yin, Yi Yuan, Xiaowen Han,et al. Genome-Wide Identification, Characterization, and Expression Profiling of TaDUF668 Gene Family in Triticum aestivum. Agronomy-Basel. 2023.Aug. IF=3.7（Cat#P118）
17. Zhang Yuting, Ye Yinghui, Xu Anping,et al. Prognosis stratification of patients with breast invasive carcinoma based on cysteine metabolism-disulfidptosis affinity. Journal OfCancer Research And Clinical Oncology. 2023.Jul. IF=3.6（Cat#P118）
18. Yaxi Wang, Ying Liu, Jufang Peng,et al. Regulation mechanisms underlying tail resorption in Bufo gargarizans metamorphosis. Comparative Biochemistry And Physiology D-Genomics & Proteomics. 2023.Jul. IF=3（Cat#P118）
19. Juan-Juan Zhang, Geng-Si Xi,,et al. Estrogen-related receptor functions via the 20-hydroxyecdysone and IIS/TOR signaling pathways to regulate the development and morphology changes of ant Polyrhachis vicina Roger (Hymenoptera, Formicidae). General And Comparative Endocrinology. 2023.Aug. IF=2.7（Cat#P118）
20. Guo Xiu-yin, Wu Ke-cheng, Dong Cheng-zhi,et al. Paraburkholderia flagellata sp. nov. and Paraburkholderia adhaesiva sp. nov., two novel species isolated from forest soil in Dinghushan Biosphere Reserve in Guangdong, China. Antonie Van Leeuwenhoek International Journal Of General And Molecular Microbiology. 2023.Aug. IF=2.6（Cat#D133）
21. Xiaofan Xiong, Siyu Zhang, Lulu Zang,et al. Cell apoptosis in the testis of male rats is elevated by intervention with β-endorphin and the mu opioid receptor. Reproductive Biology. 2023.Jul. IF=2.1（Cat#P118）
22. Qiushuang Ji, Ke Zhang, Na Cao,et al. Highly efficient overexpression and purification of multisubunit tethering complexes in Saccharomyces cerevisiae. Protein Expression And Purification. 2023.Aug. IF=1.6（Cat#D205）
06 其他系列產(chǎn)品
1. Yan Liang, Jingge Zhang, Chenlu Xu,et al. Biomimetic Mineralized CRISPR/Cas RNA Nanoparticles for Efficient Tumor-Specific Multiplex Gene Editing. Acs Nano. 2023.Jul. IF=17.1（Cat#M015）
2. Meng Xiaodan, Zhang Zhiyong, Wang Huali,et al. Multi-scale analysis provides insights into the roles of ureide permeases in wheat nitrogen use efficiency. Journal Of Experimental Botany. 2023.Jul. IF=6.9（Cat#T111）
3. Hangyu Guo, Yaqin Zhang, Fange Kong,et al. A Cas12a-based platform combined with gold nanoparticles for sensitive and visual detection of Alternaria solani. Ecotoxicology And Environmental Safety. 2023.Jul. IF=6.8（Cat#VA10252）
4. Zhao Jia, Liu Hongbin, Hong Zhixian,et al. Tanshinone I specifically suppresses NLRP3 inflammasome activation by disrupting the association of NLRP3 and ASC. Molecular Medicine. 2023.Jul. IF=5.7（Cat#C101）
5. Ruiling Zhuo, Yong Chen, Mengyang Xing,et al. Ena Proteins Respond to PacC-Mediated pH Signaling Pathway and Play a Crucial Role in Patulin Biosynthesis. Journal Of Fungi. 2023.Jul. IF=4.7（Cat#E110）
